Bronstein, Gewirtz & Grossman, LLC is investigating potential claims on behalf of purchasers of Protalix BioTherapeutics, Inc. (“Protalix” or “the Company”) (NYSE: PLX). Investors who purchased Protalix securities are encouraged to obtain additional information and assist the investigation.

The investigation concerns whether Protalix has violated federal securities laws.

Investigation Details

On October 17, 2025, Protalix and Chiesi Global Rare Diseases, Protalix’s partner in “the development, production and commercialization of recombinant therapeutic proteins produced by its proprietary ProCellEx® plant cell-based protein expression system”, issued a press release “acknowledging that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a negative opinion on the request to approve the dosing regimen of 2 mg/kg body weight infused every 4 weeks (E4W) for Elfabrio (pegunigalsidase alfa, in addition to the currently approved dosing regimen of 1 mg/kg body weight infused every 2 weeks (E2W).” Following this news, Protalix’s stock price fell $0.54 per share, or 22.5%, to close at $1.86 per share on October 17, 2025.

What’s Next?

If you are aware of any facts relating to this investigation or purchased Protalix securities, you can assist this investigation. You can also contact Peretz Bronstein or his client relations manager, Nathan Miller, of Bronstein, Gewirtz & Grossman, LLC: 332-239-2660